Clinical Nurse III - PICC

City of Hope

Irvine, CA

Job posting number: #7332639 (Ref:10034374)

Posted: April 15, 2026

Job Description

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

Position Summary:

City of Hope is seeking a skilled and experiencedPICC Nurseto join our healthcare team. The PICC Nurse is responsible for the assessment, insertion, and management of peripherally inserted central catheters (PICC lines) to ensure safe and effective intravenous access for patients requiring long-term IV therapy. This role includes patient education, coordination with the healthcare team, and adherence to infection control and safety protocols.The schedule for this opportunity is for full-time, 12-hour shifts, and day shifts.

As a successful candidate, you will:

  • Assess patients to determine the need for PICC line placement.
  • Perform ultrasound-guided PICC line insertions, ensuring proper placement and functionality.
  • Adhere to sterile technique and infection prevention protocols during line insertion.
  • Evaluate patient history, diagnosis, and treatment plan to select the appropriate vascular access.
  • Monitor PICC lines for complications such as infection, occlusion, or thrombosis.
  • Collaborate with physicians and other healthcare providers to ensure appropriate PICC line management.
  • Educate patients and families on the care and maintenance of PICC lines, including how to prevent infection.
  • Maintain accurate and timely documentation of PICC line placement, assessment, and management in the patient's medical record.
  • Report any complications or issues related to PICC lines to the medical team promptly.
  • Work closely with interdisciplinary teams, including physicians, nurses, and pharmacists, to develop and execute patient care plans.
  • Coordinate with radiology and laboratory departments for imaging and blood work related to PICC line insertion and maintenance.

Your qualifications should include:

  • Bachelor’s Degree or Master’s degree in Nursing is required
  • Current California RN license
  • Minimum of three (3) years related experience as a RN, demonstrated competency in PICC insertion using ultrasound guidance
  • Basic Life Support (BLS) CPR Card through American Heart Association
  • Specialized training in PICC line insertion using ultrasound guidance (highly preferred)
  • Successful completion of accredited class in PICC line insertion and management (highly preferred)
  • Certification in vascular access (e.g., VA-BC) (highly preferred)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, pleaseClick Here.

Salary / Pay Rate Information:
Pay Rate: $61.65 - $89.40 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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Job posting number:#7332639 (Ref:10034374)
Application Deadline:Open Until Filled
Employer Location:City of Hope
Duarte,California
United States
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